About
Concepts
Our research focuses on complex natural products synthesized by living organisms using enzymes, with the aim of proposing original strategies for the enzymatic synthesis of unexplored natural products.
The three key words in our research are "creation", "exploration", and "design": 1) create complex molecules by controlling enzyme functions, 2) thoroughly investigate the functions of enzymes that catalyze characteristic chemical reactions discovered in the process of creation, and 3) design the functions of enzymes that we have focused on. By designing and creating enzymes with new functions, we hope to break through one of the limitations of enzyme-based "synthesis" and propose an original strategy for the synthesis of unexplored molecules.
To achieve this, we need to actively integrate cutting-edge technologies. For this reason, we are also actively promoting interdisciplinary fusion with professors from other universities.
Equipments
Organic chemistry experiments
Overview: Equipment for the synthesis, purification, and analysis of natural products and the derivatives is available.
Equipments: rotary evaporator, vacuum pump, liquid chromatograph, HPLC, UPLC, HPLC-MS, UPLC-MS, GC-MS, NMR etc.
Biochemical experiments
Overview: Equipment for microbial transformation and enzyme purification is available.
Equipments: clean bench, thermal cycler, centrifuge, incubator, AKTA, etc.