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Minami-Kudo research group
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Institute of Science Tokyo
Minami-Kudo research group
日本語
|
English
HOME
About
Research
Member
Publication
Article
Review
Books
Gallery
Link
Access / Contact
OB・OG
Publication
Publication
Article
Article
2024
"Engineering the Substrate Specificity of (S)-β-Phenylalanine Adenylation Enzyme HitB"
Wang D; *Miyanaga, A; Chisuga, T; *Kudo, F; *Eguchi, T
ChemBioChem
25
,
e202400383
(2024)
.
DOI: 10.1002/cbic.202400383
"The Post-Polyketide Synthase Modification Mechanism in Hitachimycin Biosynthesis"
*Kudo, F; Tsuboi, K; Ikezaki, M; Nagayama, D; Kawamura, K; Ando, T; Miyanaga, A; *Eguchi, T
ChemBioChem
25
,
e202400405
(2024)
.
DOI: 10.1002/cbic.202400405
"Bioinformatics-guided reconstitution of biosynthetic machineries of fungal eremophilane sesquiterpenes"
Sato, Y.; Shi, X.; Ye, Y.; Domon, S.; Takino, J.; Ozaki, T.; Liu, C.; Oikawa, H.*; Minami, A.*
ACS Chem. Biol.
19
,
861-865
(2024)
.
DOI: 10.1021/acschembio.4c00040
国際共同研究;叶先生(華中科技大学)、劉先生(東北林業大学)
"Subcellular compartmentalized localization of transmembrane proteins essential for production of fungal cyclic peptide cyclochlorotine"
Katayama, T.; Jiang, Y.; Ozaki, T.*; Oikawa, H.*; Minami, A.*; Maruyama, J.*
Biosci. Biotechnol. Biochem.
88
,
1279-1288
(2024)
.
DOI: 10.1093/bbb/zbae122
異分野融合:丸山先生(東京大学)、尾崎先生(東北大学)
"Versatile filamentous fungal host highly-producing heterologous natural products developed by genome editing-mediated engineering of multiple metabolic pathways"
Saito, N.; Katayama, T.; Minami, A.; Oikawa, H.; Maruyama, J.*
Commun. Biol.
7
,
1263
(2024)
.
DOI: 10.1038/s42003-024-06958-0
異分野融合:丸山先生(東京大学)
2023
"Structural Basis of Transient Interactions of Acyltransferase VinK with the Loading Acyl Carrier Protein of the Vicenistatin Modular Polyketide Synthase"
*Miyanaga, A; Kawada, K; Chisuga, T; Kudo, F; *Eguchi, T
Biochemistry
62
,
1
,
17-21
(2023)
.
DOI: 10.1021/acs.biochem.2c00645
"Acyltransferase Domain Exchange between Two Independent Type I Polyketide Synthases in the Same Producer Strain of Macrolide Antibiotics"
*Kudo, F; Kishikawa, K; Tsuboi, K; Kido, T; Usui, T; Hashimoto, J; Shin-ya, K; Miyanaga, A; *Eguchi, T
ChemBioChem
24
,
e202200670
(2023)
.
DOI: 10.1002/cbic.202200670
"Unique Initiation and Termination Mechanisms Involved in the Biosynthesis of a Hybrid Polyketide-Nonribosomal Peptide Lyngbyapeptin B Produced by the Marine Cyanobacterium Moorena bouillonii"
*Kudo, F; Chikuma, T; Nambu, M; Chisuga, T; Sumimoto, S; Iwasaki, A; Suenaga, K; Miyanaga, A; *Eguchi, T
ACS Chem. Biol.
18
,
4
,
875-883
(2023)
.
DOI: 10.1021/acschembio.3c00011
"Structure-Based Analysis of Transient Interactions between Ketosynthase-like Decarboxylase and Acyl Carrier Protein in a Loading Module of Modular Polyketide Synthase"
Chisuga, T; Murakami, S; *Miyanaga, A; Kudo, F; *Eguchi, T
ACS Chem. Biol.
18
,
6
,
1398-1404
(2023)
.
DOI: 10.1021/acschembio.3c00151
"Structural Basis of Amide-Forming Adenylation Enzyme VinM in Vicenistatin Biosynthesis"
*Miyanaga, A; Nagata, K; Nakajima, J; Chisuga, T; Kudo, F; *Eguchi, T
ACS Chem. Biol.
18
,
11
,
2343-2348
(2023)
.
DOI: 10.1021/acschembio.3c00517
"Oxidative bicyclic ring system formation involving indole diterpene biosynthesis: Remarkable substrate tolerance of a prenyltransferase and flavoprotein oxidase"
Liu, Y.; Ozaki, T.; Minami, A.*; Oikawa, H.*
Tetrahedron Lett.
117
,
154374
(2023)
.
DOI: 10.1016/j.tetlet.2023.154374
"A fungal sesquiterpene biosynthesis gene cluster critical for mutualist-pathogen transition in Colletotrichum tofieldiae"
Hiruma, K.*; Aoki, S.; Takino, J.; Higa, T.; Utami, Y. D.; Shiina, A.; Okamoto, M.; Nakamura, M.; Kawamura, N.; Ohmori, Y.; Sugita, R.; Tanoi, K.; Sato, T.; Oikawa, H.; Minami, A.; Iwasaki, W.; Saijo, Y.
Nat. Commun.
14
,
5228
(2023)
.
DOI: 10.1038/s41467-023-40867-w
異分野融合:晝間先生(東京大学)
"Total biosynthesis of melleolides from Basidiomycota fungi: Mechanistic analysis of the multi-functional GMC oxidase Mld7"
Fukaya, M.#; Nagamine, S.#; Ozeki, M.; Matsuyama, T.; Sato, M.; Miyamoto, K.; Kawagishi H.; Watanabe, K.; Ozaki, T.; Uchiyama, M.; Oikawa, H.*; Minami, A.*
Angew. Chem. Int. Ed.
62
,
e202308881
(2023)
.
DOI: 10.1002/anie.202308881
異分野融合:河岸先生(静岡大学)、内山先生(東京大学)
2022
"Structural Insight into the Reaction Mechanism of Ketosynthase Like Decarboxylase in a Loading Module of Modular Polyketide Synthases"
Chisuga, T; Nagai, A; *Miyanaga, A; Goto, E; Kishikawa, K; Kudo, F; *Eguchi, T.
ACS Chem. Biol.
17
,
1
,
198-206
(2022)
.
DOI: 10.1021/acschembio.1c00856
"Mechanism of S-Adenosyl-L-methionine C-Methylation by Cobalamin-dependent Radical S-Adenosyl-L-methionine Methylase in 1-Amino-2-methylcyclopropanecarboxylic Acid Biosynthesis"
*Kudo, F; Minato, A; Sato, S; Nagano, N; Maruyama, C; Hamano, Y. Hashimoto, J; Kozone, I; Shin-ya, K; *Eguchi, T
Org. Lett.
24
,
49
,
8975-8979
(2022)
.
DOI: 10.1021/acs.orglett.2c03555
"Heterologous expression of a polyketide synthase ACRTS2 in Aspregillus oryzae produces host selective ACR-toxins: Co-production of minor metabolites"
Kotani, A.; Ozaki, T.*; Takino, J.; Mochizuki, S.; Akimitsu, K.; Minami, A.*; Oikawa, H.*
Biosci. Biotechnol. Biochem.
86
,
287-293
(2022)
.
DOI: 10.1093/bbb/zbab214
異分野融合:秋光先生(香川大学)
"Biosynthetic machineries of anthraquionones and bisanthraquinones in Talaromyces islandicus"
Fukaya, M.; Ozaki, T.; Minami, A.*; Oikawa, H.*
Biosci. Biotechnol. Biochem.
86
,
435-443
(2022)
.
DOI: 10.1093/bbb/zbac009
"Structure and biosynthesis of ribosomal lipopeptide antibiotic albopeptins"
Oikawa, H.*; Mizunoue, Y.; Nakamura, T.; Fukushi, E.; Jiang, Y.; Ozaki, T.; Minami, A.; Isono, K.
Biosci. Biotechnol. Biochem.
86
,
717-723
(2022)
.
DOI: 10.1093/bbb/zbac039
日本農芸化学会欧文誌論文賞受賞
"Elucidation of late-stage biosynthesis of phomoidride: Proposal of cyclization mechanism affording characteristic 9-membered ring of fungal dimeric anhydride"
Yamamoto, S.; Matsuyama, T.; Ozaki, T.*; Takino, J.; Sato, H.; Uchiyama, M.*; Minami, A.*; Oikawa, H.*
J. Am. Chem. Soc.
144
,
20998-21004
(2022)
.
DOI: 10.1021/jacs.2c09308
異分野融合:内山先生(東京大学)、尾崎先生(東北大学)
2021
"Biosynthetic studies of phomopsins unveil posttranslational installation of dehydroamino acids by UstYa family proteins"
Sogahata, K.; Ozaki, T.*; Igarashi, Y.; Naganuma, Y.; Liu, C.; Minami, A.*; Oikawa, H.*
Angew. Chem. Int. Ed.
60
,
25729-25734
(2021)
.
DOI: 10.1002/anie.202111076
"One-pot Enzymatic Synthesis of 2-Deoxy-scyllo-inosose from D-Glucose and Polyphosphate"
*Kudo, F; Mori, A; Koide, M; Yajima, R; Takeishi, R; Miyanaga, A; *Eguchi, T
Biosci. Biotechnol. Biochem.
85
,
1
,
108_114
(2021)
.
DOI: 10.1093/bbb/zbaa025
"Stepwise Post-glycosylation Modification of Sugar Moieties in Kanamycin Biosynthesis"
*Kudo, F; Kitayama, Y; Miyanaga, A; Numakura, M; *Eguchi, T
ChemBioChem
22
,
9
,
1668_1675
(2021)
.
DOI: 10.1002/cbic.202000839
"Mutational Biosynthesis of Hitachimycin Analogs Controlled by the β-Amino Acid-Selective Adenylation Enzyme HitB"
*Kudo, F; Takahashi, S; Miyanaga, A; Nakazawa, Y; Nishino, K; Hayakawa, Y; Kawamura, K; Ishikawa, F; Tanabe, G; Iwai, N; Nagumo, Y; Usui, T; *Eguchi, T
ACS Chem. Biol.
16
,
3
,
539_547
(2021)
.
DOI: 10.1021/acschembio.1c00003
"Complex Structure of the Acyltransferase VinK and the Carrier Protein VinL with a Pantetheine Cross-linking Probe"
*Miyanaga, A; Ouchi, R; Kudo, F; *Eguchi, T
Acta Crystallographica Section F
77
,
294-302
(2021)
.
DOI: 10.1107/S2053230X21008761
"Biochemical and Mutational Analysis of Radical S-Adenosyl-L-Methionine Adenosylhopane Synthase HpnH from Zymomonas mobilis Reveals that the Conserved Residue Cysteine-106 Reduces a Radical Intermediate and Determines the Stereochemistry"
Sato, S; *Kudo, F; Rohmer, M; *Eguchi, T
Biochemistry
60
,
38
,
2865-2874
(2021)
.
DOI: 10.1021/acs.biochem.1c00536
"Biosynthesis of cyclochlorotine: Identification of the genes involved in oxidative transformations and intramolecular O,N-transacylation"
Jiang, Y.; Ozaki, T.*; Liu, C.; Igarashi, Y.; Ye, Y.; Tang, S.; Ye, T.; Maruyama, J.; Minami, A.*; Oikawa, H.*
Org. Lett.
23
,
2616-2620
(2021)
.
DOI: 10.1021/acs.orglett.1c00525
異分野融合:丸山先生(東京大学)
"Genome-based discovery of enantiomeric pentacyclic sesterterpenes catalyzed by the fungal bifunctional terpene synthase"
Jiang, L.; Zhang, X.; Sato, Y.; Zhu, G.; Minami, A.; Zhang, W.; Ozaki, T.; Zhu, B.; Wang, Z.; Wang, X.; Lv, K.; Zhang, J.; Wang, Y. -H.; Gao, S. -S.; Liu, C.; Hsiang, T.; Zhang, L.; Oikawa, H.*; Liu, X.*
Org. Lett
23
,
4645-4650
(2021)
.
DOI: 10.1021/acs.orglett.1c01361
国際共同研究:劉先生(華東理工大学)
"Biochemistry-guided prediction of absolute configuration of fungal reduced polyketide"
Takino, J.; Kotani, A.; Ozaki, T.; Peng, W.; Yu, J.; Guo, Y.; Mochizuki, S.; Akimitsu, K.; Hashimoto, M.; Ye, T.*; Minami, A.*; Oikawa, H.*
Angew. Chem. Int. Ed.
60
,
23403-23411
(2021)
.
DOI: 10.1002/anie.202110658
国際共同研究:叶先生(北京大学深セン大学院)
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